Stephen Johnston

Stephen is an accomplished drug discovery executive with a proven record of leading and transforming scientific and business operations within therapeutic research.  Prior to DoriNano, he served as the Head of Technologies within the Center for the Development of Therapeutics at the Broad Institute, the culmination of 18 years at the Broad Institute engaging in cutting-edge biological research with faculty and external partners.  In this role, he led the development and launch of the RABIT platform (rapid, automated discovery of VHH binders targeting diverse epitopes) including leading business development efforts exceeding $2.5m with domestic and international partners in the platform's first year.  This encompassed conceptualizing and executing on the value proposition, developing competitive intelligence and strategy, and detailing the financial model for the platform.  Previously, he helped establish the strategy and business model for the Broad Institute's Drug Repurposing Hub, enabling a self-sustaining differentiating scientific resource utilized by 200+ projects since its inception.

His experience spans scientific (VHH discovery, analytical chemistry/ADME, high-throughput screening, laboratory automation, high-content imaging, sample management, and data informatics) and operational (technical operations, financial operations, portfolio management) spheres with experience and expertise across both small molecule and VHH therapeutic environments.  At DoriNano, this ability to bring together science and business, especially his experience growing awareness of, building collaborations around, and raising funds for the advancement of novel technologies, will be invaluable as DoriNano positions its DNA origami platform and pipeline assets for success.

Stephen received his BS from Davidson College, PhD (analytical chemistry in the lab of James Jorgenson) from the University of North Carolina-Chapel Hill, and MBA from the Massachusetts Institute of Technology.  Stephen has co-authored 16 publications with more than 3,600 citations.